A COMPARTMENTAL MODEL OF THE CAMP/PKA/MAPK PATHWAY IN BIO-PEPA

A compartmental model of the cAMP/PKA/MAPK pathway in Bio-PEPA

The vast majority of biochemical systems involve the exchange of information between different compartments, either in the form of transportation or via the intervention of membrane proteins which are able to transmit stimuli between bordering compartments.The correct quantitative handling of compartments is, therefore, extremely important when mod

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Climate response to the 8.2 ka event in coastal California

Abstract A fast-growing stalagmite from the central California coast provides a high-resolution record of climatic changes synchronous with global perturbations resulting from the catastrophic drainage of proglacial Lake Agassiz at ca.8.2 ka.High frequency, large amplitude variations in carbon isotopes during the 8.2 ka event, coupled with pulsed i

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The Early Paleozoic history of the Cuyania (greater Precordillera) terrane of western Argentina: evidence from geochronology of detrital zircons from Middle Cambrian sandstones

U-Pb geochronology of large detrital zircons populations is a powerful tool for interpreting sandstone provenance.Here, Seeds it is applied to three Middle Cambrian sandstones from the Precordillera of Argentina with the purpose of using the provenance interpretations to test paleogeographic and paleotectonic models proposed for the Cuyania or Prec

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